RISK FACTORS LEADING TO MAJOR LOWER LIMB AMPUTATIONS IN DIABETIC PATIENTS WITH FOOT ULCERS

Purpose: Foot ulceration in persons with diabetes is the most frequent precursor to amputation, which impairs their activities. The aim of this study was describe factors that lead amputation a diabetic foot, and propose management strategy prevent major amputation.
 Methods: Cross-sectional conducted at Qazi Hussain Ahmad Hosptial, Nowshera Pakistan, from Jan, 2016, July 2021, comprised patients either gender having type 1 or 2 foot ulcers. wounds were assessed according Wagner wound staging sepsis evaluated terms local infection wound, leukocytosis osteomyelitis bone. glycemic control these on presentation by measuring glaciated hemoglobin levels. Data analyzed using SPSS 22.
 Findings: Out Of 450 patients, 263(60%) males 187(40%) females. Majority 193(43%) aged 40-70 years. All 450(100%) underwent some amputation. all amputations, 301(67%) done poor glycaemic presentation, 187(41%) those stage 4 wound. Local infection, increased total leukocyte count bone showing features significantly associated risk lower extremity amputations (p<0.05).
 Conclusion: With proper early treatment, majority could be avoided